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Riboflavin-UVA collagen cross-linking for the treatment of acanthamoeba keratitis

   
@article{AES4692,
	author = {Choul Yong Park and Roy S. Chuck},
	title = {Riboflavin-UVA collagen cross-linking for the treatment of acanthamoeba keratitis},
	journal = {Annals of Eye Science},
	volume = {4},
	number = {2},
	year = {2019},
	keywords = {},
	abstract = {In this review, recent studies regarding riboflavin-ultraviolet A (UVA) collagen cross-linking for the treatment of acanthamoeba keratitis (AK) were reviewed. English written studies about acanthamoeba, keratitis, riboflavin and collagen cross-linking were retrieved from PubMed search engine (www.ncbi.nlm.nih.gov/pubmed). Although there were significant numbers of cases reporting the effectiveness of riboflavin-UVA collagen cross-linking in AK, experimental studies (in vivo and in vitro) failed to verify amoebicidal or cysticidal effect of riboflavin-UVA collagen cross-linking. In conclusion, the efficacy of riboflavin-UVA collagen cross-linking for the treatment of AK is still debatable. It is necessary to conduct a prospective case-control study for clear guidance for clinicians.},
	issn = {2520-4122},	url = {https://aes.amegroups.org/article/view/4692}
}